Gastroenterology

Gastrointestinal endoscopy and the acquisition of tissue samples are essential for the diagnosis and treatment of various diseases of the digestive system.   A range of tissue samples are extracted and are analyzed under a microscope using a Hematoxylin & Eosin stain, and in some cases, immunohistochemical and special stains to identify cancerous cell abnormalities. If cancer is present, it can be localized to the exact region from the location of the tissue extraction. 

This test identifies patients with high risk Barrett’s esophagus that have an increased probability of progression to esophageal cancer.  The test employs cytology, immunohistochemistry (IHC), and fluorescence in situ hybridization (FISH) methodologies, in concert, to differentiate between patients that require aggressive invervention versus candidates for reduced surveillance.  The test can be performed on both biopsies and brushings from patients with Barrett's esophagus.  The biomarkers associated with BE FISH can be ordered as a panel (BE FISH+) or individually based on the needs of the ordering physician.